Indian J Physiol Pharmacol. Oct;45(4) In vivo hepatoprotective activity of active fraction from ethanolic extract of Eclipta alba leaves. Singh B(1). Request PDF on ResearchGate | Hepatoprotective activity of Eclipta alba Hassk. against paracetamol induced hepatocellular damage in mice | The effect of. The hepatoprotective activity of different extracts of whole plant Eclipta alba was investigated against CCl4 induced hepatic damage inmale albino rat.
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Keywords Carbon tetrachloride, Hepatoprotective activity, Eclipta alba, Silymarin.
The possible hepatoprotective activity of Eclipta alba whole plant extract against CCl4| Abstract
Hepatoprotective effects of Calotropis gigantea extract against carbon tetrachloride induced liver injury in rats. Animals were kept starved over night on 90 th day. As regards the total proteins the mg dose of Eclipta alba brings the protein value at most equal to the normal rats. Hepatoprotective activity of Boerhaavia diffusa L.
In vivo hepatoprotective activity of active fraction from ethanolic extract of Eclipta alba leaves.
As regards the total lipid the value got increased in 50 mg dose but at higher dose, it got decreased which is still much higher then the albba lipid values in the control rats. Antihepatotoxic activity of eclipta alba, tephrosia purpurea and boerhaavia diffusa.
The results of the study confirmed the hepatoprotective activity of aqueous extracts of E. Values were little less as compare to the Silymerin. The phospholipids content in serum registered a significant like that of liver showed a deamination in CCl4 administered group.
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They were then mechanically powdered and sieved. In vivo hepatoprotective activity of active fraction from ethanolic extract of Eclipta alba leaves.
They were fed with pallets of Golden feed, New Eckipta. Liver homogenates were also subjected to various biochemical estimation.
Drug Dev Ind Pharm. But it was noiticed that the recovery beginning as soon as the plant extract was given. Rest parameters were found hepatoprotectige be all most normal level when three different doges of the compound of the Eclipta alba were given to the CCl4 induced hepatotoxic rat.
However, the dose adjustments may be necessary to optimize the similar hepatoprotective efficacy in clinical settings. Indian J Exp Biol.
The level of significance was set at 0. They were given hepatoprogective week time to get acclimatized with the laboratory conditions.
Biochanin A protects against acute carbon tetrachloride-induced hepatotoxicity in rats.
The results were comparable to that of silymarin. One way analysis of variance ANOVA followed activityy Scheffes test was applied for determinig the statistical significance of difference in enzymes, protein and lipids levels between different group. Thus, it is quite clear that, total lipid, cholesterol and phospholipids were found to be increased against the control group Ist.
Mehra and Handa, On the next day the blood was collected by making an incession by jugular vein to collect the blood. Protective effects of pterostilbene against acetaminophen-induced hepatotoxicity in rats. Hassk has been widely used in India for the traditional treatment of liver disorders Chopra et al.
The possible hepatoprotective activity of Eclipta alba whole plant extract against CCl4
Article Tools Print this article. Girish C, Pradhan SC. Actuvity and characterization of phyto-vesicles of wedelolactone for hepatoprotective activity. Regarding ALP the value remained to be activitj bit higher as compared to the control group and Silymerin treatment. Shrivastava performed taxonomic identification and the voucher specimen was deposited in the herbarium of our laboratory for future reference vide access no. The observations of these dose, clearly indicat the involvement of heptoprotective active principles in Eclipta alba.